Plummer-Vinson syndrome as an uncommon cause of progressive dysphagia

Plummer–Vinson syndrome (PVS) is a very rare condition associated with iron-deficiency anemia and an increased risk of squamous cell carcinoma of the upper gastrointestinal tract. We present the case of a 65-year-old woman with progressive dysphagia in whom endoscopic evaluation revealed cervical esophageal webs. Treatment with endoscopic dilation and iron supplementation led to clinical resolution. This case highlights the importance of considering PVS in the differential diagnosis of dysphagia and of implementing targeted management with appropriate follow-up.