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September 3, 2026Journal of Food Composition and AnalysisOpen Access

An integrated chemometric workflow for botanical origin discrimination and electronic tongue profiling of processing-related taste variation in Coptidis Rhizoma

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Authors

ZMZicheng MaHQHuixian QingCLChuang Li

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Overview

Analytical study demonstrates accurate origin discrimination and taste profiling in Coptidis Rhizoma, indicating a reliable quality control workflow for complex herbal medicines.

Key Points

  • To establish an integrated chemometric workflow combining spectroscopy, mass spectrometry, and electronic tongue analysis for botanical origin discrimination and processing-related taste profiling in Coptidis Rhizoma.
  • Evaluated FT-IR and NIR spectroscopy with various preprocessing, variable-selection techniques (VIP, CARS), and supervised classification models to discriminate C. chinensis, C. deltoidea, and C. teeta.
  • Conducted UPLC-Q-TOF-MS/MS fingerprinting coupled with CP-ANN modeling to identify origin-specific chemical markers and utilized an electronic tongue (E-tongue) to profile taste variations between raw and processed samples.
  • NIR models combining second-derivative preprocessing with VIP or CARS variable selection achieved 100% classification accuracy in distinguishing the three botanical origins.
  • UPLC-Q-TOF-MS/MS coupled with CP-ANN identified six alkaloids as origin-discriminating markers, with C. chinensis exhibiting the highest relative levels of most quantified alkaloids.
  • E-tongue sensor analysis effectively separated raw and processed samples, showing that wine-processed forms induced the largest overall sensory shift, primarily across umami, saltiness, and general taste dimensions.

Cite This Study

Ma et al. (2026) studied this question.

synapsesocial.com/papers/6a9935e5636c6408cfa7e808https://doi.org/10.1016/j.jfca.2026.109491
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