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Secondary analysis reveals medication distress and self-efficacy drive medicine concerns in older adults with polypharmacy, highlighting targets for nursing interventions.
Purpose: This study aimed to investigate medication self-efficacy, health information interaction, and distress related to medication in older adults with polypharmacy and to determine the factors influencing concerns about medicines. Methods: This study was a secondary analysis based on a 2025 study and a total of 197 participants were included. Participants' concerns about medicines, medication self-efficacy, health information interaction, distress related to medication, and sociodemographic characteristics were measured. Descriptive statistics, one-way analysis of variance, Pearson correlation coefficients, and multiple regression analysis were conducted. Results: Statistically significant correlations were found among the key variables, namely medication self-efficacy, health information interaction, distress related to medication, and concerns about medicines. Distress related to medication (β=.52, p<.001), medication self-efficacy (β=-.33, p<.001), and health information interaction (β=-.21, p=.003) were identified as significant factors influencing concerns about medicines in older adults with polypharmacy. The explanatory power of these variables was 49%. Conclusion: Medication self-efficacy, health information interaction, and distress related to medication were key variables influencing concerns about medicines. Nursing interventions aimed at reducing concerns about medicines should focus on decreasing medication-related distress, enhancing medication self-efficacy, and providing health information through telenursing interactions.
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Kim et al. (2026) studied this question.
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