Cohort study finds vigorous activity alongside low food resources associates with higher depressive symptom risk in older adults, highlighting the need to evaluate material context.
Physical activity is generally associated with lower depression risk, but an intensity-only questionnaire cannot distinguish the context in which activity occurs. We examined whether considering household food-related consumption alongside a self-reported vigorous-activity indicator helped characterize subsequent depressive-symptom risk. We analyzed Harmonized China Health and Retirement Longitudinal Study (CHARLS) Version D, with Wave 3 as baseline and Wave 4 as follow-up. Adults aged ≥ 45 years with baseline CES-D10 < 10 were cross-classified by vigorous activity and low per-capita household food-related consumption (lowest quartile; ≤50 yuan/person/week). Survey-weighted modified Poisson models estimated adjusted risk ratios (RRs), and marginal standardization estimated absolute risks. Weighted analyses included 4,161 participants. Compared with no vigorous activity/adequate resources, vigorous activity/low resources was associated with higher incident depressive-symptom risk (RR, 1.31; 95% CI, 1.07–1.60). Adjusted risks were 29.0% versus 22.1%, a difference of 6.82% points (95% CI, 1.33–12.31). Formal multiplicative and additive interaction estimates were compatible with the null. Results were broadly consistent across key sensitivity analyses, although some alternative definitions were less precise. Self-reported vigorous activity combined with low household food-related consumption identified a higher-risk joint profile. The findings do not indicate that vigorous activity is harmful, and formal statistical interaction with low-resource status was not supported. These results suggest that material context should be considered when interpreting questionnaire-defined vigorous activity.
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Luo et al. (2026) studied this question.
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