Key result
Post-mortem intervals of up to 10 hours in rat myocardium resulted in rapid glycogen depletion and longer sarcomere lengths after one hour, with minimal changes to mitochondria.
Authors
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Post-mortem delays may confound myocardial histology; leaves open optimal fixation timing in cardiac research models.
Hibbs et al. (1963) studied post-mortem changes in myocardium. post-mortem interval vs. immediately after death was evaluated on autolytic change. Post-mortem intervals of up to 10 hours in rat myocardium resulted in rapid glycogen depletion and longer sarcomere lengths after one hour, with minimal changes to mitochondria.
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