What question did this study set out to answer?

To assess the cognitive and psychomotor effects of a standardized aqueous extract of Withania somnifera in healthy human participants.

December 11, 2013Pharmacognosy ResearchOpen Access

Effect of standardized aqueous extract of Withania somniferaon tests of cognitive and psychomotor performance in healthy human participants

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Authors

UPUsharani PingaliNizam's Institute of Medical Sciences RPRaveendranadh PilliNizam's Institute of Medical Sciences NFNishat FatimaDr. A.P.J. Abdul Kalam Technical University

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Implication

Randomized double-blind crossover trial reveals improved cognitive and psychomotor reaction times in healthy males, suggesting its therapeutic potential for cognitive impairment.

Key Points

To assess the cognitive and psychomotor effects of a standardized aqueous extract of Withania somnifera in healthy human participants.
Prospective, double-blind, placebo-controlled crossover study in N=20 healthy male participants.
Participants received two 250 mg capsules twice daily of dried aqueous extract of roots and leaves of Withania somnifera or matching placebo for 14 days, separated by a 14-day washout period.
Cognitive and psychomotor performance was evaluated pre-dose on day 1 and 3 hours post-dose on day 15 using computerized psychometric tests.
Withania somnifera extract produced significant improvements in reaction times during simple reaction, choice discrimination, digit symbol substitution, digit vigilance, and card sorting tests compared to placebo.
No significant treatment effect was observed on the finger tapping test.

Cite This Study

Pingali et al. (2013) studied this question.

synapsesocial.com/papers/6a993f4a3c2ace4a27748ed5 https://doi.org/10.4103/0974-8490.122912

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Implication

Randomized double-blind crossover trial reveals improved cognitive and psychomotor reaction times in healthy males, suggesting its therapeutic potential for cognitive impairment.

Effect of standardized aqueous extract of Withania somniferaon tests of cognitive and psychomotor performance in healthy human participants

Discussion

Member takes

Implication

Key Points

Cite This Study

Effect of standardized aqueous extract of Withania somniferaon tests of cognitive and psychomotor performance in healthy human participants

Discussion

Member takes

Implication

Key Points

Cite This Study

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