Key result
Myocardial perfusion defects were associated with a significantly higher 2-year rate of cardiac events compared to normal perfusion in hemodialysis patients (78% vs. 15%, P < 0.001).
Why the study?
Do myocardial perfusion defects on SPECT and elevated CRP levels predict cardiac events in hemodialysis patients?
Population
77 hemodialysis patients
Comparison
Thallium-201 single-photon emission computed… vs Normal myocardial perfusion and/or lower CRP…
Design
Cohort
Follow-up
2 years
Authors
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May support SPECT for cardiac risk stratification in hemodialysis; leaves open whether targeted interventions improve outcomes.
Cohort (n=77)
Do myocardial perfusion defects on SPECT and elevated CRP levels predict cardiac events in hemodialysis patients?
Absolute Event Rate: 78% vs 15%
p-value: p=< 0.001
Myocardial perfusion SPECT and elevated CRP levels are independent predictors of 2-year cardiac events in hemodialysis patients, identifying those at high risk for coronary atherosclerosis progression.
Hase et al. (2006) conducted a cohort in Hemodialysis (n=77). Myocardial perfusion defect vs. Normal perfusion was evaluated on Cardiac event (cardiac death, non-fatal acute coronary syndrome, or hospitalization for acute ischemic heart failure) (p=< 0.001). Myocardial perfusion defects were associated with a significantly higher 2-year rate of cardiac events compared to normal perfusion in hemodialysis patients (78% vs. 15%, P < 0.001).
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