Key result
Coronary stent placement was associated with a lower rate of recurrent cardiac events compared to PTCA (30% vs. 71%) in hemodialysis patients with obstructive coronary disease.
Why the study?
Does coronary stent placement reduce recurrent cardiac events compared to PTCA in hemodialysis patients with obstructive coronary disease?
Cohort (n=19)
Does coronary stent placement reduce recurrent cardiac events compared to PTCA in hemodialysis patients with obstructive coronary disease?
Absolute Event Rate: 30% vs 71%
Coronary stent placement produces more favorable clinical outcomes with fewer recurrent cardiac events compared to PTCA in hemodialysis patients with obstructive coronary disease.
May support stenting over PTCA in hemodialysis patients; hypothesis-generating and requires randomized confirmation.
This retrospective study examined the utilization of coronary stent placement versus PTCA in hemodialysis patients with obstructive coronary disease. Prior studies have demonstrated suboptimal results with PTCA owing primarily to high rates of restenosis. We identified 19 hemodialysis patients who received a percutaneous coronary intervention who were matched with individuals without renal failure undergoing same vessel revascularization. Our study found that 71% of hemodialysis patients receiving PTCA had a recurrent cardiac event defined by subsequent angina, myocardial infarction, or cardiac death. At follow-up, 30% of patients who received stent placement had recurrent cardiac events. Intracoronary stent placement is both safe and feasible and produces more favorable clinical outcomes in the management of coronary disease in hemodialysis patients.
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Malanuk et al. (2001) conducted a cohort in Obstructive coronary disease in hemodialysis patients (n=19). Coronary stent placement vs. PTCA was evaluated on Recurrent cardiac event (subsequent angina, myocardial infarction, or cardiac death). Coronary stent placement was associated with a lower rate of recurrent cardiac events compared to PTCA (30% vs. 71%) in hemodialysis patients with obstructive coronary disease.
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