Key result
Previously diagnosed diabetes was associated with increased odds of probable depression compared to normal glucose regulation (OR 1.61; 95% CI 1.39-1.87).
Why the study?
Is impaired glucose regulation or diabetes associated with depression in middle-aged and elderly Chinese adults?
Population
229,047 community-dwelling adults aged ≥ 40 years from 25 centres in China
Comparison
Impaired glucose regulation, newly diagnosed… vs Normal glucose regulation
Design
Cross-sectional
Authors
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May support depression screening in known diabetes; leaves open causality and directionality in Chinese adults.
Cross-Sectional (n=229,047)
Yes
Is impaired glucose regulation or diabetes associated with depression in middle-aged and elderly Chinese adults?
Odds Ratio: 1.61 (95% CI 1.39–1.87)
Absolute Event Rate: 1.8% vs 1.1%
Previously diagnosed diabetes, particularly when treated with insulin, is associated with a higher prevalence of depression in Chinese adults, whereas newly diagnosed diabetes and impaired glucose regulation are not.
Sun et al. (2014) conducted a cross-sectional in Diabetes and depression (n=229,047). Previously diagnosed diabetes vs. Normal glucose regulation was evaluated on Probable depression (OR 1.61, 95% CI 1.39-1.87). Previously diagnosed diabetes was associated with increased odds of probable depression compared to normal glucose regulation (OR 1.61; 95% CI 1.39-1.87).
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