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BACKGROUND: Excimer laser phototherapeutic keratectomy has generated considerable interest in treating superficial corneal and scleral pathology. The excimer laser is also used to treat recurrent corneal epithelial erosions. METHODS: With the MEL 50 Aesculap-Meditec 193-nanometer argon-fluoride excimer laser, we treated 74 eyes of 73 individuals, who suffered from posttraumatic, therapy-resistant, recurrent corneal epithelial erosions. We used the excimer laser in spot-mode under manual guidance. Only in those eyes where the erosion was covered with loose bullous epithelium did we remove the epithelium mechanically prior to surgery. The postoperative follow-up period ranged from 6 months to 4 years. RESULTS: Of the 74 eyes, 55 (74.43%) eyes were recurrence-free. One eye developed superficial haze in the treated area. No other complications occurred. CONCLUSION: Phototherapeutic keratectomy in recurrent epithelial erosions is a promising treatment, especially in recalcitrant cases with the erosion over the entrance pupil. Photoablation allows a fast reepithelialization of the affected area and quick relief for painful symptoms. (Refract Corneal Surg. 1993;9:419-424.) RÉSUMÉ INTRODUCTION: La photokératectomie thérapeutique au laser excimer a produit beaucoup d'intérêt comme traitement de la pathologie superficielle cornéenne et sclerale. On utilise le laser excimer aussi pour soigner les érosions cornéennes. MÉTHODES: Chez 73 individus qui souffraient d'érosions cornéennos post-traumatiques et résistantes à la thérapie, nous avons soigné 74 yeux avec le laser excimer MEL 50 Aesculap-Meditec 193 nm à l'argon fluoride. Le laser est positionné en mode de point ("spot mode") et guidé manuellement. Nous avons enlevé !'epithelium mécaniquement en pré-opératoire seulement dans le cas des érosions couvertes d'un epithelium bulleux et desserré. Le suivi moyen post-opératoire variait entre 6 mois et 4 ans. RÉSULTATS: Cinquante-cinq des 74 yeux (74.4%) n'avaient aucun rechute. Un oeil a montré une brume légère et superficielle dans la région traitée. Il n'y avait aucune autre complication. CONCLUSION: La photokératectomie thérapeutique est un traitement prometteur chez les érosions récidivantes, spécialement celles situées sur la pupille. La réepithéliasation se fait rapidement et entraine le soulagement prompt des symptômes douloureux. (Translated by Rob Mack, MD, Iowa City, la.) SOMMARIO PREMESSA: La cheratectomia fototerapeutica con laser ad eccimeri ha suscitato un notevole interesse per il trattamento di patologie superficiali della cornea e della sclera. Il laser ad eccimeri viene anche utilizzato per trattare erosioni corneali epiteliali recidivanti. METODI: Con il laser ad eccimeri a fluoruro di argon Aesculap-Meditec MEL 50 che emette a 193-nm abbiamo trattato 74 occhi di 73 pazienti, che presentavano erosioni corneali epiteliali recidivanti post-traumatiche, resistenti alla terapia medica. Abbiamo utilizzato il laser ad eccimeri in maniera spot, con controlio manuale. Nei soli casi in cui l'erosione era ricoperta da epitelio non aderente, abbiamo rimosso meccanicamente l'epitelio prima dell'intervento. Il periodo di followup postoperatorio è risultato compreso tra 6 mesi e 4 anni.
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Dausch et al. (1993) studied this question.
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