Key result
The correlation coefficient between the predicted regional cerebral blood flow obtained from MRA and 123I-IMP scintigraphy was 0.68, suggesting MRA is a suitable substitute for evaluating cerebral blood flow in moderate internal carotid artery stenosis.
Why the study?
Understanding cerebral blood flow is warranted to manage cerebral hyperperfusion syndrome after CAS, but whether MRA can delineate cerebral blood flow compared with nuclear medicine scans remained to be determined.
Does MRA signal intensity accurately predict cerebral blood flow compared to 123I-IMP scintigraphy in patients with moderate internal carotid artery stenosis?
Observational (n=42)
No
Does MRA signal intensity accurately predict cerebral blood flow compared to 123I-IMP scintigraphy in patients with moderate internal carotid artery stenosis?
Answers are grounded in this paper and cite their sources.
MRA signal intensity correlates with 123I-IMP scintigraphy and may serve as a noninvasive, convenient alternative for estimating cerebral blood flow in patients with moderate internal carotid artery stenosis.
Carotid artery stenting （CAS） is a procedure used in the treatment of internal carotid artery stenosis, a condition that can lead to cerebral infarction. Cerebral hyperperfusion syndrome is among the post-CAS complications. Thus, to ensure postoperative control, understanding the cerebral blood flow is warranted. Nuclear medicine scan is used for the quantitative assessment of cerebral blood flow; however, since magnetic resonance imaging allows assessment of the cerebral artery, it is often used pre- and postoperatively. In the present study, we compared magnetic resonance angiography （MRA） with nuclear medicine scan to determine if MRA can delineate the cerebral blood flow in patients with CAS. The correlation coefficient between the predicted regional cerebral blood flow obtained from MRA and 123I-IMP was 0.68. Moreover, the concordance rate was high. As a result, the MRA test may be used as an alternative imaging study, and it was found to be a reference value in clinical practice.
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Sakiyama et al. (2023) conducted an observational in Internal carotid artery stenosis (n=42). Magnetic resonance angiography (MRA) vs. 123I-IMP scintigraphy was evaluated on Correlation between predicted regional cerebral blood flow obtained from MRA and 123I-IMP (Correlation coefficient 0.68). The correlation coefficient between the predicted regional cerebral blood flow obtained from MRA and 123I-IMP scintigraphy was 0.68, suggesting MRA is a suitable substitute for evaluating cerebral blood flow in moderate internal carotid artery stenosis.
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