Key result
Addition of Piedmontese myostatin alleles (P1 and P2) consistently increased muscle through hyperplasia, decreased fat, and increased adjusted efficiency, though many changes were not linear.
Population
618 F2 crossbred calves from Hereford, Limousin, and Piedmontese sires
Comparison
Limousin and Piedmontese sire breeds, and the… vs Hereford-cross F2 calves and Piedmontese-cross…
Design
Preclinical, Sires were bred at random to crossbred cows
Follow-up
From birth to slaughter
Authors
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Informs livestock breeding for muscle yield; leaves open translational relevance to human therapeutics.
Differences in muscularity, particularly the presence of the msP allele, significantly affect growth and body composition traits in crossbred calves.
Short et al. (2002) studied Muscularity and lean tissue growth (n=618). Piedmontese myostatin allele (msP) and sire breed vs. Hereford-cross F2 calves and P0 genotype (zero copies of msP) was evaluated on Traits measured from birth to slaughter (muscle, fat, growth, feed conversion). Addition of Piedmontese myostatin alleles (P1 and P2) consistently increased muscle through hyperplasia, decreased fat, and increased adjusted efficiency, though many changes were not linear.
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