Why the study?
Does inhalation of high concentration oxygen improve umbilical vein PO2 in healthy pregnant women undergoing Cesarean section?
Does inhalation of high concentration oxygen improve umbilical vein PO2 in healthy pregnant women undergoing Cesarean section?
High concentration oxygen inhalation during Cesarean section increases umbilical vein PO2 only when maternal PaO2 is between 250 and 400 mmHg, with potential declines at higher levels.
Target maternal PaO2 to 250-400 mmHg during Cesarean section to optimize umbilical vein PO2; challenges routine hyperoxia and supports titration trials.
We give high concentration of oxygen during Cesarean section in the hope of giving the fetus more oxygen.In order to assess the validity of the practice, we measured the umbilical arterial and venous blood O2 tention.The study was performed in 32 healthy pregnant women undergoing Cesarean section with spinal anesthesia by making them inhale 21%, 50%, or 90% O2. The maternal PaO2 (MAPO2) was compared with the umbilical artery PO2 (UAPO2) and umbilical vein PO2 (UVPO2) obtained immediately after delivery.The results showed that UVPO2 change little with MAPO2 up to 250mmHg, while UVPO2 increased linearly with MAPO2 between 250 and 400mmHg, but some cases showed declining UVPO2 with MAPO2 above 400mmHg.
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Otani et al. (1983) studied this question.
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