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June 1, 1979Journal of Clinical InvestigationOpen Access

Specific Inhibition of the Polymorphonuclear Leukocyte Chemotactic Response to Hydroxy-Fatty Acid Metabolites of Arachidonic Acid by Methyl Ester Derivatives

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Authors

EGEdward J. GoetzlAsahikawa Medical College HospitalFVFrank H. ValoneProtagonist Therapeutics (United States)VRVernon N. ReinholdUniversity of New Hampshire

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Goetzl et al. (1979) studied this question.

synapsesocial.com/papers/6a995a2a13e19562d9f0dfbehttps://doi.org/10.1172/jci109412
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis.1975 · 588 citations
  2. 2Preparation and Spectral Properties of 12-Hydroxyl Eicosatetraenoic Acid (HETE)1978 · 23 citations
  3. 3Chemotactic and Chemokinetic Stimulation of Human Eosinophil and Neutrophil Polymorphonuclear Leukocytes by 12-L-Hydroxy-5,8,10-Heptadecatrienoic Acid (HHT)1978 · 149 citations
  4. 4A Chemotactic Receptor for VAL(ALA)-GLY-SER-GLU on Human Eosinophil Polymorphonuclear Leukocytes1976 · 14 citations
  5. 5Inhibition of in Vivo and in Vitro Neutrophil Responses to Chemotactic Factors by a Competitive Antagonist1978 · 71 citations