Key result
Treatment with a gluten-free diet and/or immunosuppression was associated with clinical improvement or stabilization in 84% of treated patients with anti-GAD ataxia.
Why the study?
To report the clinical characteristics and treatment of patients with progressive cerebellar ataxia associated with anti-GAD antibodies.
Does a gluten-free diet or immunosuppression improve clinical symptoms and MR spectroscopy in patients with anti-GAD ataxia?
Observational (n=50)
No
Does a gluten-free diet or immunosuppression improve clinical symptoms and MR spectroscopy in patients with anti-GAD ataxia?
In patients with anti-GAD ataxia, there is a high prevalence of gluten sensitivity, and treatment with a strict gluten-free diet or immunosuppression leads to clinical improvement or stabilization in the majority of cases.
No takes yet. Share an insight, caveat, or question.
May aid recognition of anti-GAD ataxia; leaves open optimal management pending prospective studies.
Hadjivassiliou et al. (2020) conducted an observational in Anti-GAD ataxia (n=50). Gluten-free diet and/or immunosuppression was evaluated on Clinical improvement or stabilisation. Treatment with a gluten-free diet and/or immunosuppression was associated with clinical improvement or stabilization in 84% of treated patients with anti-GAD ataxia.
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