Key result
Among ideal candidates who developed a postoperative myocardial infarction, prior treatment with beta-blockers was associated with lower in-hospital mortality (OR 0.19; 95% CI 0.04-0.87).
Why the study?
Does beta-blocker therapy before infarction reduce in-hospital mortality in ideal candidates who develop postoperative MI?
Population
72 patients who developed a postoperative myocardial infarction after major noncardiac surgery between…
Comparison
Beta-blocker therapy administered before the… vs No beta-blocker therapy administered before the…
Design
Cohort
Follow-up
In-hospital
Authors
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Should not yet change perioperative beta-blocker practice; leaves open potential survival benefit in postoperative MI pending randomized confirmation.
Cohort (n=72)
No
Does beta-blocker therapy before infarction reduce in-hospital mortality in ideal candidates who develop postoperative MI?
Odds Ratio: 0.19 (95% CI 0.04–0.87)
Appropriate perioperative use of beta-blockers in ideal candidates may significantly reduce in-hospital mortality even among patients who subsequently develop a postoperative myocardial infarction.
Lindenauer et al. (2004) conducted a cohort in Postoperative myocardial infarction (n=72). Beta-blocker therapy vs. No beta-blocker therapy was evaluated on In-hospital mortality (OR 0.19, 95% CI 0.04-0.87). Among ideal candidates who developed a postoperative myocardial infarction, prior treatment with beta-blockers was associated with lower in-hospital mortality (OR 0.19; 95% CI 0.04-0.87).
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