Key result
Perioperative beta-blockade in patients undergoing major noncardiac surgery reduced myocardial ischemia (NNT 2.5-6.7) and cardiac or all-cause mortality (NNT 3.2-8.3).
Why the study?
Does perioperative beta-blockade reduce myocardial ischemia, myocardial infarction, and mortality in patients undergoing major noncardiac surgery?
Systematic Review
Does perioperative beta-blockade reduce myocardial ischemia, myocardial infarction, and mortality in patients undergoing major noncardiac surgery?
Perioperative beta-blockade may reduce cardiac morbidity and mortality in high-risk patients undergoing major noncardiac surgery, though optimal protocols remain unclear.
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Supports perioperative beta-blockade in major noncardiac surgery; confirms mortality benefit while optimal protocols remain unclear.
Auerbach et al. (2002) conducted a systematic review in Major noncardiac surgery. Perioperative beta-blockade was evaluated on Myocardial ischemia, myocardial infarction, and cardiac or all-cause mortality. Perioperative beta-blockade in patients undergoing major noncardiac surgery reduced myocardial ischemia (NNT 2.5-6.7) and cardiac or all-cause mortality (NNT 3.2-8.3).
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