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The effect of partial recycle of microbial cells on the operation of a chemostat has been investigated for two fermentations. Stable steady states without partial cell recycle were obtained for the conversion of D‐sorbitol to L‐sorbose by Gluconobacter oxydans subsp. suboxydans 1916B and for the conversion of glucose to 2‐ketogluconic acid by Serratia marcescens NRRL B‐486. The employment of partial cell recycle dramatically increased product formation rates for both fermentations.
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Bull et al. (1981) studied this question.
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