Key result
In patients aged 40-64 with carotid atherosclerosis, decreased atherosclerotic plaque echogenicity was significantly associated with increased body weight index (r=-0.359, P<0.0001).
Why the study?
To identify clinical and laboratory indexes related to atherosclerotic plaque echogenicity assessed by grey-scale median in patients aged 40-64 years.
Observational
Effect estimate: r=-0.359
p-value: p=<0.0001
In patients aged 40-64 with carotid atherosclerosis, increased body weight index and waist circumference are associated with decreased plaque echogenicity, suggesting a potential link between central obesity and plaque vulnerability.
Central obesity links to lower carotid plaque echogenicity; hypothesis-generating for vulnerability, needs prospective confirmation before clinical use.
Aim To identify clinical and laboratory indexes related with the atherosclerotic plaque (ASP) echogenicity based on results of the analysis of grey-scale median (GSM) in patients aged 40-64 years.Material and methods The study included patients aged 40-64 years with carotid atherosclerosis. The carotid duplex scanning was performed for all patients. The GSM analysis of obtained images was performed with the Adobe Photoshop CS6 software.Results Atherosclerotic cardiovascular diseases were found in 31 (21.4 %) patients. Correlation analysis determined inverse interrelationships between GSM and the body weight index (BWI) (r=-0.359; p<0.0001), waist circumference (r=-0.357; p<0.0001), and levels of uric acid (r=-0.244; p=0.021) and glucose (r=-0.205; p=0.032). According to the regression, statistically significant correlations remained between GSM and BWI as well as the waist circumference after the adjustment for sex and age.Conclusion In patients with carotid atherosclerosis aged 40-64 years, the decrease in ASP GSM was associated with increases in BWI and waist circumference.
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Genkel et al. (2021) conducted an observational in Carotid atherosclerosis. Body weight index and waist circumference was evaluated on Atherosclerotic plaque echogenicity (grey-scale median) (r=-0.359, p=<0.0001). In patients aged 40-64 with carotid atherosclerosis, decreased atherosclerotic plaque echogenicity was significantly associated with increased body weight index (r=-0.359, P<0.0001).
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