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January 31, 2025Acta Paediatrica

Novel Insights in Perioperative Neuroprotection in Neonatal Congenital Heart Disease

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Why the study?

The perioperative period of neonatal cardiac surgery contributes to lifelong neurological injury, prompting the need to describe emerging neuroprotective strategies in neonatal CHD.

Population

Neonatal patients with congenital heart disease

Design

Review

Key result

Emerging strategies for neuroprotection in the perioperative period in neonatal patients with congenital heart disease are described to address neurodevelopmental deficits.

Authors

SGSonia Garcés‐SánchezÁSÁlvaro Soláz-GarcíaJGJosé L. López Guillén

Discussion

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Member takes

Overview

May support early neurodevelopmental screening in CHD; hypothesis-generating for intervention trials.

Structured PICO

P
Population
Neonatal patients with congenital heart disease
I
Intervention
Perioperative neuroprotection strategies
O
Outcome
Neurodevelopmental outcomes and neurological injury

This review highlights emerging perioperative neuroprotective strategies to mitigate lifelong neurological injury in neonates undergoing surgery for congenital heart disease.

Cite This Study

Garcés‐Sánchez et al. (2025) conducted a review in Congenital heart disease. Neuroprotective strategies was evaluated. Emerging strategies for neuroprotection in the perioperative period in neonatal patients with congenital heart disease are described to address neurodevelopmental deficits.

synapsesocial.com/papers/6a99626b38b9b8dc3720116dhttps://doi.org/10.1111/apa.70006
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