Why the study?
Takotsubo cardiomyopathy can lead to left ventricular thrombus, and this report discusses the management of these cases.
Case Report (n=1)
No
Answers are grounded in this paper and cite their sources.
A 3-month course of apixaban successfully resolved an incidentally discovered left ventricular thrombus and allowed for recovery of cardiac function in a patient with takotsubo cardiomyopathy.
Takotsubo cardiomyopathy is a potentially lethal condition characterized by transient regional systolic dysfunction in the absence of coronary artery ischemia. This syndrome predominantly affects postmenopausal women and is often preceded by physical or emotional stress and often presents with symptoms of acute coronary syndrome, chest pain, and shortness of breath. Although the effects can be transient, takotsubo cardiomyopathy still results in an 8-12% rate of in-hospital mortality, with cardiogenic shock being the most common cause of death. There are known risk factors that increase the likelihood of a patient developing a left ventricular thrombus during the clinical course. The management of these cases is discussed in this report.
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Beckmann et al. (2023) conducted a case report in Takotsubo cardiomyopathy with left ventricular thrombus (n=1). Anticoagulation (Heparin followed by Apixaban) was evaluated on Resolution of LV thrombus and recovery of ejection fraction.
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