Key result
Severe aortic stenosis in elderly patients undergoing hip fracture repair did not significantly increase the 30-day rate of postoperative cardiac events compared to controls (18.7% vs 11.8%).
Why the study?
Does severe aortic stenosis increase the risk of 30-day postoperative cardiac events in elderly patients undergoing surgical repair of hip fracture?
Cohort (n=120)
Does severe aortic stenosis increase the risk of 30-day postoperative cardiac events in elderly patients undergoing surgical repair of hip fracture?
Absolute Event Rate: 18.7% vs 11.8%
Elderly patients with severe aortic stenosis can safely undergo hip fracture repair with 30-day mortality and cardiac event rates comparable to patients without severe aortic stenosis.
May support proceeding with hip fracture repair in severe aortic stenosis; leaves open need for randomized confirmation.
Background: The perioperative assessment and management of elderly patients with hip fracture and significant aortic stenosis (AS) is an increasingly common clinical problem with little data available to guide perioperative management. Objectives: It was the aim of this study to examine the incidence of perioperative events in an elderly population of patients with severe AS undergoing repair of hip fracture as compared with controls without severe AS. Methods: Patients over the age of 70 with an echocardiographic diagnosis of severe AS defined as an aortic valve area ≤1.0 cm2 who underwent surgery for hip fracture repair were retrospectively identified. An age-matched group of patients without a history of AS who underwent surgical repair of hip fracture was the control group. The primary outcome of the incidence of postoperative cardiac events defined as death, acute coronary syndrome or pulmonary edema within 30 days was compared. Results: Thirty-two patients with AS (median age 84.5 years, range 72–94; 27 females and 5 males) and 88 controls (median age 86 years, range 80–95; 67 females and 21 males) were entered into the study. There were no significant differences between the AS group and controls for 30-day mortality (6.2 vs. 6.8%) or for the total cardiac event rate (18.7 vs. 11.8%). Conclusions: Our results demonstrate that elderly patients with severe AS can safely undergo repair of hip fractures with a mortality and morbidity comparable with a control population. These patients should not be denied surgery on the basis of their aortic valve disease.
No takes yet. Share an insight, caveat, or question.
Leibowitz et al. (2009) conducted a cohort in Hip fracture (n=120). Severe aortic stenosis vs. Age-matched patients without a history of AS was evaluated on Postoperative cardiac events (death, acute coronary syndrome or pulmonary edema) within 30 days. Severe aortic stenosis in elderly patients undergoing hip fracture repair did not significantly increase the 30-day rate of postoperative cardiac events compared to controls (18.7% vs 11.8%).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: