Key result
Administration of Digoxin-specific antibody fragments and Advanced Pediatric Life Support successfully resuscitated a 12-week-old female in asystolic cardiac arrest from digoxin poisoning.
Why the study?
Can digoxin-specific antibody fragments and standard APLS successfully resuscitate a pediatric patient in asystolic cardiac arrest secondary to digoxin toxicity?
Case Report (n=1)
Can digoxin-specific antibody fragments and standard APLS successfully resuscitate a pediatric patient in asystolic cardiac arrest secondary to digoxin toxicity?
This case report demonstrates that a pediatric patient in asystolic cardiac arrest due to digoxin toxicity can be successfully resuscitated with standard APLS and digoxin-specific antibody fragments, achieving full neurological recovery.
We report the first case of a child with known cardiac disease who presented in full cardiac arrest secondary to digoxin poisoning and was successfully resuscitated. A 12-week-old female presented 1-week status post surgical repair of a congenital heart anomaly in asystolic cardiac arrest. The patient was successfully resuscitated with standard Advanced Pediatric Life Support. A toxic digoxin level returned, Digoxin-specific antibody fragments (Digibind, Fab) were administered, and all signs and symptoms of toxicity resolved. The patient was discharged 6 days after presentation with full neurological recovery.
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Eyal et al. (2005) conducted a case report in Digoxin poisoning and asystolic cardiac arrest (n=1). Digoxin-specific antibody fragments (Digibind, Fab) and Advanced Pediatric Life Support was evaluated on Survival and neurological recovery. Administration of Digoxin-specific antibody fragments and Advanced Pediatric Life Support successfully resuscitated a 12-week-old female in asystolic cardiac arrest from digoxin poisoning.
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