Depression-Dependent Dyskinesias in Two Cases of Manic-Depressive Illness

WE report the occurrence of state-dependent dyskinesia in two rapidly cycling manic-depressive patients. Marked oral, buccal, lingual, and associated dyskinesias consistently recurred during depression and essentially disappeared during mania over the course of repeated mood cycles. Reports of simultaneous improvements in dyskinesias and mood after electroconvulsive therapy also suggest a relation between mood and dyskinesias.1 , 2 MethodsTwo patients met the criteria for manic-depressive, circular (bipolar Type I) illness. Nurses who were "blind" to medications and, initially, to the interest in the possible association of dyskinesias and mood phase rated the patients according to a global scale that includes scores for . . .