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The Second International Ankle Symposium was a multidisciplinary conference focused on topics related to ankle instability and associated pathologies and was held on the campus of the University of Delaware in October 2004 and brought together over 75 clinicians and scientists from disciplines such as physical therapy, athletic training, orthopedics, podiatry, and biomechanics. This special supplement to the Journal of Orthopaedic & Sports Physical Therapy includes a summary statement, synopses of 5 plenary lectures, and the abstracts of the original research presentations from the second International Ankle Symposium. J Orthop Sports Phys Ther 2005; 35(5):A1–A28. doi:10.2519/jospt.2005.0301
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