Key result
Contrast-enhanced CT incidentally reveals rare double superior vena cava draining directly into left atrium.
Why the study?
PLSVC draining into the left atrium can cause a right-to-left shunt and compromise oxygen delivery, highlighting the importance of recognizing rare vascular anomalies that may remain clinically silent.
Case Report (n=1)
A rare anatomical variant of a persistent left superior vena cava draining directly into the left atrium can be diagnosed non-invasively using contrast-enhanced CT and may remain clinically silent due to compensatory physiological mechanisms.
Alerts clinicians to consider this rare CT variant despite absent hypoxemia; case report leaves open questions of prevalence and management.
Persistent left superior vena cava (PLSVC) is an uncommon developmental variation of the thoracic venous system, sometimes accompanied by a duplicated superior vena cava (SVC). While often asymptomatic when draining into the right atrium, drainage toward the left atrium could lead to a right-to-left shunt and potential compromise of whole-body oxygen delivery. This report describes a 48-year-old male patient with hypertension and chronic tobacco use who was evaluated for dyspnea and leg edema. Imaging revealed a double SVC, where the left-sided vessel connected directly to the left atrium. Despite this anomaly, the patient exhibited no significant hypoxemia or cyanosis, likely due to long-term compensatory mechanisms. This report underscores the need to consider vascular anomalies in imaging interpretation, particularly when findings are incidental. It also underscores the role of contrast-enhanced CT in identifying rare anatomical variants and the potential for such anomalies to remain clinically silent despite physiological significance.
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A 2025 study conducted a case report in Persistent left superior vena cava (PLSVC) (n=1). Anomalous persistent left superior vena cava draining into the left atrium was evaluated. Contrast-enhanced CT incidentally identified a rare double superior vena cava with the persistent left-sided vessel draining directly into the left atrium in a patient without significant hypoxemia.
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