Key result
The abstract outlines a systematic review and meta-analysis of electrocardiographic parameters in pediatric arrhythmogenic cardiomyopathy but does not report any quantitative results.
Why the study?
Diagnostic algorithms for arrhythmogenic cardiomyopathy have limitations in children, where high-tech methods are difficult, and data on ventricular arrhythmia features in pediatric populations are lacking.
Meta-Analysis
This systematic review and meta-analysis aims to characterize electrocardiographic parameters and ventricular arrhythmias in pediatric patients with arrhythmogenic cardiomyopathy to aid in non-invasive diagnosis.
VA predominate in pediatric ACM with depolarization changes in ~75%; leaves open refined ECG criteria for non-classical forms pending validation.
Arrhythmogenic cardiomyopathy (ACM) is a rare genetic disease characterized by the development of life-threatening ventricular arrhythmias and impaired ventricular systolic function due to fibrofatty infiltration of the myocardium. Currently, the Task Force 2010 criteria and the Padua criteria are proposed for the diagnosis of this disease. However, despite the multiparametric approach, there are certain limitations of the presented algorithms for disease establishment, especially in children. Carrying out such high-tech diagnostic methods as endomyocardial biopsy and magnetic resonance imaging is extremely difficult in the pediatric population. In this regard, the study and application of electrocardiography becomes extremely relevant in children. In addition, there are no data on the features of ventricular arrhythmias in ACM in the pediatric population. In this systematic review with meta-analysis, we studied the features of ventricular arrhythmias and electrocardiographic parameters in various ACM types.
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Alekseeva et al. (2022) conducted a meta-analysis in Arrhythmogenic cardiomyopathy. Electrocardiographic parameters and ventricular arrhythmias was evaluated on Features of ventricular arrhythmias and electrocardiographic parameters. The abstract outlines a systematic review and meta-analysis of electrocardiographic parameters in pediatric arrhythmogenic cardiomyopathy but does not report any quantitative results.
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