Key result
High density lipoprotein cholesterol levels in middle age were not related to longevity or all-cause mortality, although men who died from coronary heart disease tended to have lower HDL.
Why the study?
Is high density lipoprotein cholesterol (HDL) in middle age related to longevity or coronary heart disease mortality in healthy men?
Population
217 healthy executive men aged 45 to 55 at entry in 1948
Design
Cohort
Follow-up
Up to 35 years (1948 to 1983)
Authors
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HDL levels in middle-aged men should not inform longevity counseling; leaves open selective CHD mortality link for prospective study.
Cohort (n=217)
Is high density lipoprotein cholesterol (HDL) in middle age related to longevity or coronary heart disease mortality in healthy men?
HDL cholesterol levels in middle-aged men do not predict overall longevity, although lower HDL is associated with coronary heart disease mortality.
Ancel Keys (1988) conducted a cohort in Healthy (n=217). High density lipoprotein cholesterol (HDL) was evaluated on Longevity (all-cause mortality). High density lipoprotein cholesterol levels in middle age were not related to longevity or all-cause mortality, although men who died from coronary heart disease tended to have lower HDL.
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