Key result
Tricuspid annular plane systolic excursion (TAPSE) was significantly lower in critically-severe COVID-19 patients (17.6 mm) compared to severe patients (20.4 mm, P=0.0068) and healthy controls (23.8 mm, P<0.0001).
Why the study?
To investigate right heart function in COVID-19 patients with ARDS.
Population
49 COVID-19 patients with ARDS and age-matched healthy volunteers
Comparison
Severe vs critically-severe COVID-19 patients vs healthy controls
Design
Retrospective study
Authors
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Right heart assessment may aid risk stratification in COVID-19 ARDS; leaves open whether targeted RV support improves outcomes.
Observational (n=74)
No
Absolute Event Rate: 17.6% vs 20.4%
p-value: p=0.0068
Right ventricular dysfunction, indicated by reduced TAPSE and enlarged cardiac cavities, is highly prevalent in critically-severe COVID-19 pneumonia with ARDS and correlates with disease severity.
Li et al. (2020) conducted an observational in COVID-19 pneumonia with ARDS (n=74). Critically-severe COVID-19 pneumonia vs. Severe COVID-19 pneumonia was evaluated on Tricuspid annular plane systolic excursion (TAPSE) (p=0.0068). Tricuspid annular plane systolic excursion (TAPSE) was significantly lower in critically-severe COVID-19 patients (17.6 mm) compared to severe patients (20.4 mm, P=0.0068) and healthy controls (23.8 mm, P<0.0001).
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