The synthesis of 6‐deoxy‐6‐18F‐α‐D‐galactopyranose (XXII)

This is the authors' abstract. We don't add key points for this paper.

The synthesis of 6‐deoxy‐6–18F‐α‐D‐galactopyranose from the 6‐tosyl‐1,2:3,4‐di‐O‐isopropylidene derivative, using tetraethyl‐ammonium fluoride‐18F is described. The synthesis requires 4–4 1/2 hours for completion. The radiochemical yield (activity in compound/starting activity. corrected for decay) is about 15%. Thus 3–4% of the starting 18F– activity is present at the time of delivery, in approximately 0.2 mg of product.