Key result
In a model experiment of arterial stenosis, mean-square wall pressure showed strong Reynolds-number dependence at low Reynolds numbers, and maximum intensity distance depended on jet velocity and fluid viscosity.
This model study demonstrates that the intensity and location of fluctuating mechanical stress downstream of a stenosis depend on Reynolds number, jet velocity, and fluid viscosity.
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Model data on post-stenotic wall pressure leave open clinical translation; extends hemodynamic understanding pending in vivo validation.
The fluctuating mechanical stress imposed upon the arterial-wall downstream of a stenosis by turbulent blood flow was studied in a model experiment. The dependence of mean-square wall pressure and spectral density of wall pressure upon Reynolds number, diameter ratio, and distance from the stenosis was obtained. The mean-square pressure was found to have strong Reynolds-number dependence at low Reynolds number, and the distance downstream of the stenosis at which the mean-square fluctuating pressure reaches its maximum intensity was found to depend upon jet velocity and fluid viscosity only. A high Reynolds-number scaling of the spectral density of wall pressure was obtained.
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Jeffrey J. Fredberg (1977) studied Arterial stenosis and vascular murmurs. Turbulent blood flow downstream of a stenosis was evaluated on Mean-square wall pressure and spectral density of wall pressure. In a model experiment of arterial stenosis, mean-square wall pressure showed strong Reynolds-number dependence at low Reynolds numbers, and maximum intensity distance depended on jet velocity and fluid viscosity.
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