After screening several fungal isolates obtained from Venezuelan soils, the isolate IR-94MF1 of Penicillium rugulosum was selected for its high mineral phosphate solubilizing activity (Mps ) with hydroxyapatite. Mutants with altered (Mps 3 ) or amplified activity (Mps ) were obtained by UV irradiation of conidia. When glucose was used as the sole C source by the fungus, gluconic acid was associated with the hydroxyapatite activity. In solid media, in comparison to glucose and maltose, sucrose appeared to be the best C source for the solubilization of hydroxy-apatite and FePO R .
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Reyes et al. (1999) studied this question.
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