Answers are grounded in this paper and cite their sources.
Clinical isolates of Escherichia coli collected from 1991 through 2005 at a tertiary-care center were studied for qnr and aac(6')-Ib-cr genes. Isolates bearing aac(6')-Ib-cr emerged in 1998, coinciding with an increase in ciprofloxacin resistance. The presence of aac(6')-Ib-cr was multiclonal and was associated with the presence of extended-spectrum beta-lactamases.
No takes yet. Share an insight, caveat, or question.
Warburg et al. (2008) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: