Answers are grounded in this paper and cite their sources.
Existing experimental models of cardiac lesion do not allow precise reproducible dimensions of injury with complete safeness of surrounding tissues and cannot answer the tremendous question for heart cell therapy: are the implanted cells unable to influence the heart healing process or do the conditions in the injured heart prevent their complete development and integration? 60 rats were used for elaborating an alternative technique of cardiac lesion.
No takes yet. Share an insight, caveat, or question.
Coulic et al. (2015) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: