Key result
Ropivacaine 0.5% provided a significantly faster onset of sensory block (4.93 vs 8.47 minutes) and longer duration of sensory block (9.03 vs 7.18 hours) compared to bupivacaine 0.5%.
Why the study?
Does 0.5% ropivacaine improve the onset and duration of sensory and motor block compared to 0.5% bupivacaine in patients undergoing upper limb surgeries?
RCT (n=60)
Double-blind
Computerized chart
No
Does 0.5% ropivacaine improve the onset and duration of sensory and motor block compared to 0.5% bupivacaine in patients undergoing upper limb surgeries?
Absolute Event Rate: 4.93% vs 8.47%
p-value: p=0.000
Ropivacaine 0.5% provides faster onset and longer duration of sensory and motor blockade compared to bupivacaine 0.5% for supraclavicular brachial plexus block, with a similar safety profile.
Supports preferring ropivacaine 0.5% for supraclavicular blocks in upper limb surgery; extends RCT evidence guiding regional anesthesia choices.
Background: Present study was undertaken to evaluate the clinical efficacy of 0.5% ropivacaine for supraclavicular bronchial plexus block for upper limb surgeries and comparing it with 0.5% bupivacaine in terms of characteristics of supraclavicular blockade and side effects. Methods: The design was a prospective double blind randomized study enrolling 60 patients of either sex, ASA I and II, were randomly allocated into two groups in which supraclavicular brachial plexus block was performed with nerve stimulator using 30 ml of ropivacaine 0.5% and bupivacaine 0.5% respectively. The onset and duration of sensory and motor block and possible adverse events were recorded.Results: Ropivacaine had earlier onset of sensory and motor blockade compared to bupivacaine. The duration of sensory and motor blockade was longer in group of patients treated with ropivacaine than in bupivacaine group. No statistically significant difference was found in quality of blocks in both groups. There were no adverse effects observed in the study.Conclusions: Ropivacaine 0.5% can be safely used as an alternative to bupivacaine 0.5% in supraclavicular bronchial plexus block.
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Modak et al. (2016) conducted an RCT in Upper limb orthopedic and plastic surgeries (n=60). Ropivacaine vs. 30 ml of 0.5% bupivacaine was evaluated on Onset of sensory block (minutes) (p=0.000). Ropivacaine 0.5% provided a significantly faster onset of sensory block (4.93 vs 8.47 minutes) and longer duration of sensory block (9.03 vs 7.18 hours) compared to bupivacaine 0.5%.
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