Key result
Levobupivacaine demonstrated a faster onset and longer duration of sensory and motor blockade compared to racemic bupivacaine in patients undergoing upper limb surgeries.
Why the study?
The study was performed to compare the effectiveness of bupivacaine and levobupivacaine for supraclavicular brachial plexus block in upper limb surgeries.
Does levobupivacaine improve the onset and duration of sensory and motor blockade compared to bupivacaine in patients undergoing upper limb surgeries with supraclavicular brachial plexus block?
Observational (n=100)
No
Does levobupivacaine improve the onset and duration of sensory and motor blockade compared to bupivacaine in patients undergoing upper limb surgeries with supraclavicular brachial plexus block?
Levobupivacaine provides a faster onset and longer duration of sensory and motor blockade compared to bupivacaine in supraclavicular brachial plexus blocks, with a similar safety profile.
May support levobupivacaine in supraclavicular blocks; leaves open randomized confirmation before practice change.
Background: Dexmedetomidine produces manageable hypotension and bradycardia, but the striking feature of this drug is the lack of opioid-related side effects such as respiratory depression, pruritus, nausea and vomiting. Addition of dexmedetomidine to local anaesthetic drugs during peripheral nerve blocks may also prove beneficial for surgical patients. Hence, the present study was performed to compare the effectiveness of bupivacaine and levobupivacaine for supraclavicular brachial plexus block in upper limb surgeries. Materials and Methods: The present study was conducted in the Department of Anesthesia of MGM Medical College, Navi Mumbai. The ethical clearance for the study was approved from the ethical committee of the hospital. The study was conducted on 100 patients of ASA I & II status in the age group of 18-60 years given brachial plexus block by supraclavicular approach for various upper limb surgeries, after receiving institutional ethics committee approval. Results: Levobupivacaine had a faster onset & longer duration of both sensory and motor blockade as compared to racemic bupivacaine. The hemodynamic profile of both drugs was similar and no adverse effect was found with either drug. Conclusion:We conclude that in peripheral nerve blocks where large volumes of local anaesthetic is required, levobupivacaine could be a suitable choice as it is known to have less toxic potential.
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Santosh et al. (2021) conducted an observational in Upper limb surgeries (n=100). Levobupivacaine vs. Bupivacaine was evaluated on Onset and duration of sensory and motor blockade. Levobupivacaine demonstrated a faster onset and longer duration of sensory and motor blockade compared to racemic bupivacaine in patients undergoing upper limb surgeries.
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