Changes in Acid-Base Balance of Uremic Patients During Hemodialysis 1

Patients who are acutely or chronically ill with the uremic syndrome are clinically improved fol- lowing the procedure of external hemodialysis. The exact changes responsible for this' improve- ment are not known. It has been shown that dialysis removes retained nitrogenous metabolites and returns disordered serum electrolyte con- centrations toward normal (1). The purpose of this study is to describe more precisely the changes in the acid-base balance present in uremic patients and their modification during hemodialysis.