Key result
Patients with intraluminal carotid thrombus exhibited distinctive features including thrombus formation without significant atherostenosis and clotting tendency despite heparin anticoagulation.
Case Report (n=5)
Identifies an uncommon subgroup of stroke patients with large artery thrombosis characterized by specific clinical features and suspected coagulopathy.
Answers are grounded in this paper and cite their sources.
May flag a heparin-refractory carotid thrombus subset in stroke; hypothesis-generating for coagulopathy evaluation.
We studied five patients with intraluminal carotid thrombus visualized by angiography. The distinctive clinical features included the following: thrombus formation without significant atherostenosis; peripheral and cerebral arterial thrombosis; step-wise evolution of cerebral and/or peripheral signs over a period of days to several weeks; clotting tendency despite heparin anticoagulation; and carotid or iliac artery thrombosis after thrombo-endarterectomy. These unusual features serve to identify an uncommon subgroup of stroke patients with large artery thrombosis. Pathogenesis was not established. Coagulopathy with elevated factor VIII levels was the suspected mechanism.
No takes yet. Share an insight, caveat, or question.
Pessin et al. (1986) conducted a case report in Intraluminal carotid thrombus (n=5). Intraluminal carotid thrombus was evaluated on Clinical and angiographic features. Patients with intraluminal carotid thrombus exhibited distinctive features including thrombus formation without significant atherostenosis and clotting tendency despite heparin anticoagulation.
Synapse has enriched 10 related papers. Consider them for comparative context: