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January 1, 1986Journal of Clinical PathologyOpen Access

Clinical importance of production of slime by coagulase negative staphylococci in chronic ambulatory peritoneal dialysis.

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Authors

KKKarl G. KristinssonUniversity of IcelandRSR.C. SpencerMorgan Stanley Children's HospitalCBColin B. BrownCancer Care Nova Scotia

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Implication

Clinical observation reveals pathways of bacterial colonisation and infection risk in vulnerable patients, indicating how tissue irritation facilitates microbial overgrowth.

Key Points

  • To evaluate the clinical relevance of slime-producing bacteria and identify anatomical and environmental risk factors that facilitate bacterial colonization and opportunistic infection.
  • Assessed microbial transmission and colonization across potential reservoirs, including birth canal flora and respiratory tract exposure from clinical handlers.
  • Evaluated physiological drainage defects, such as impaired nasolacrimal drainage, alongside local tissue inflammation and excess chemical antiseptic exposure.
  • Bacterial colonization is markedly facilitated when normal physiological fluid clearance is impaired by defective nasolacrimal drainage pathways.
  • Localized tissue irritation from excess topical antiseptics and preexisting inflammation promotes fluid accumulation, creating a suitable microenvironment for microbial overgrowth.

Cite This Study

Kristinsson et al. (1986) studied this question.

synapsesocial.com/papers/6a99a7d693fbc3428a54d60chttps://doi.org/10.1136/jcp.39.1.117
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1MANUAL FOR THE IDENTIFICATION OF MEDICAL BACTERIA1965 · 2,591 citations
  2. 2Coagulase negative staphylococcal infections.1985 · 11 citations
  3. 3Adherence and Growth of Coagulase-Negative Staphylococci on Surfaces of Intravenous Catheters1982 · 564 citations
  4. 4Pathogenesis and management of Staphylococcus epidermidis 'plastic' foreign body infections1984 · 52 citations
  5. 5A Plate Test for Nitrate Reduction1950 · 56 citations