Key result
Combined coronary revascularization and lung resection in 10 patients resulted in 0% operative mortality, with 7 patients alive at 12 to 38 months follow-up.
Why the study?
Is combined coronary revascularization and lung resection safe in patients with lung cancer and coexistent ischaemic heart disease?
Observational (n=10)
Is combined coronary revascularization and lung resection safe in patients with lung cancer and coexistent ischaemic heart disease?
Answers are grounded in this paper and cite their sources.
Combined coronary revascularization and lung resection can be safely performed in selected patients, with long-term results dependent on the control of the lung carcinoma.
As age and smoking are common risk factors, patients with lung cancer frequently have coexistent ischaemic heart disease. Ignoring the coronary disease results in an unacceptable operative mortality, whilst sequential coronary grafting and lung resection may prejudice the results of the resection. A series of 10 patients underwent combined coronary revascularization (average 2.9 grafts per patient) and lung resection for carcinoma (seven lobectomies, one bilobectomy, one sleeve lobectomy, and one pneumonectomy). The majority of patients had unstable angina, triple vessel or left main coronary artery stenosis and poorly staged tumours. There was no operative mortality and the average hospital stay was 20 days. Half the patients had significant peri-operative morbidity; seven are alive and well at between 12 and 38 months follow-up; but three have died of recurrent carcinoma (one with associated sepsis) at 3, 8, and 13 months. Combined coronary revascularization and lung resection can be safely performed in selected patients. The early morbidity is mainly related to the cardiac procedure and impaired respiratory function preoperatively, but the long-term results are dependent upon the control of the lung carcinoma.
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Rosalion et al. (1993) conducted an observational in Lung cancer and coexistent ischaemic heart disease (n=10). Combined coronary revascularization and lung resection was evaluated on Operative mortality. Combined coronary revascularization and lung resection in 10 patients resulted in 0% operative mortality, with 7 patients alive at 12 to 38 months follow-up.
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