Key result
Older adults with cardiovascular risk had a significantly prolonged mean response time of oxygen uptake during exercise compared to healthy older adults (83.6 vs 49.2 seconds, p=0.033).
Why the study?
Mean response time of oxygen uptake calculation by linear regression or monoexponential fitting is highly variable, whereas combining incremental and constant load exercise is more reproducible.
Does cardiovascular risk prolong the mean response time of oxygen uptake during exercise in older adults compared to healthy controls?
Cross-Sectional (n=30)
No
Does cardiovascular risk prolong the mean response time of oxygen uptake during exercise in older adults compared to healthy controls?
Older adults with cardiovascular risk factors exhibit a significantly prolonged mean response time of oxygen uptake during exercise, which inversely correlates with daily physical activity levels.
Answers are grounded in this paper and cite their sources.
Prolonged oxygen uptake response time may indicate reduced exercise tolerance in at-risk older adults; hypothesis-generating and requires prospective validation.
Background During incremental exercise (Inc-Ex), the mean response time (MRT) of oxygen uptake (V̇O2) represents the time delay before changes in muscle V̇O2 reflect at the mouth level. MRT calculation by linear regression or monoexponential (τ’) fitting of V̇O2 data are known to be highly variable, and a combination of incremental and constant load exercise (CL-Ex) is more reproducible. Methods We evaluated MRT in older adults using linear regression and combination methods. We recruited 20 healthy adults (male: 9, 69.4 ± 6.8 years) and 10 cardiovascular risk subjects (male: 8, 73.0 ± 8.8 years). On day 1, they performed Inc-Ex using a 10W/min ramp protocol, for determination of the ventilatory anaerobic threshold (VAT) using the V-slope method. On day 2, they performed Inc-Ex to VAT exercise intensity and CL-Ex for 25min total. The MRT was calculated from the CL-Ex V̇O2 average and the time at equivalent V̇O2 in the Inc-Ex. We also assessed the amount of physical activity using the International Physical Activity Questionnaire short form (IPAQ-SF). Results The MRT of healthy participants and those at cardiovascular risk were 49.2 ± 36.3 vs. 83.6 ± 45.4s (p = 0.033). Total physical activity in the IPAQ-SF was inversely correlated with MRT. Conclusion The MRT was significantly prolonged in cardiovascular risk participants compared to healthy participants, possibly related to the amount of daily physical activity. Individual MRT may be useful for adjustment of exercise intensity, but this should also be based on daily physical activity and individual condition during exercise.
No takes yet. Share an insight, caveat, or question.
Kominami et al. (2022) conducted a cross-sectional in Cardiovascular risk (n=30). Cardiovascular risk vs. Healthy older adults was evaluated on Mean response time (MRT1) of oxygen uptake (p=0.033). Older adults with cardiovascular risk had a significantly prolonged mean response time of oxygen uptake during exercise compared to healthy older adults (83.6 vs 49.2 seconds, p=0.033).
Synapse has enriched 10 related papers. Consider them for comparative context: