Key result
Breathing room air significantly increased physiologic shunting to 26% of cardiac output compared to 14% on 100% oxygen in patients following open mitral valve surgery.
Why the study?
Does heart valve replacement or repair cause significant postoperative physiologic shunting and hypoxemia in patients undergoing elective surgery?
Observational (n=18)
No
Does heart valve replacement or repair cause significant postoperative physiologic shunting and hypoxemia in patients undergoing elective surgery?
Heart valve surgery, regardless of the use of extracorporeal circulation, results in significant postoperative hypoxemia primarily due to diffuse atelectasis causing large physiologic right-to-left shunts.
Answers are grounded in this paper and cite their sources.
May exacerbate postoperative hypoxemia after mitral valve surgery; leaves open optimal oxygenation strategies in broader valve populations.
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Hedley‐Whyte et al. (1965) conducted an observational in Postoperative state following elective aortic or mitral valve surgery (n=18). Breathing room air vs. Breathing 100% oxygen was evaluated on Physiologic shunt as a percentage of cardiac output in the open mitral surgery group (p=<0.01). Breathing room air significantly increased physiologic shunting to 26% of cardiac output compared to 14% on 100% oxygen in patients following open mitral valve surgery.
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