The effect of errors of the concentration (c‐) and the light‐scattering molar mass (M‐) detector in gel permeation chromatography (GPC) on the accuracy of the determination of the molar mass distribution (MMD) was analyzed. Model calculations showed that the reliability of MMD obtained from c‐detector data and from a carefully performed calibration dependence is higher than that obtained by combining data of the M‐ and c‐detectors. A criterion of the uncertainty of the MMD determination by the GPC method with the M‐detector was suggested, and its dependence on MMD parameters of the analyzed polymer and on the magnitude of injection was investigated.
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Procházka et al. (1986) studied this question.
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