Why the study?
Group A Rotaviruses cause a substantial public health burden and high mortality in developing regions, prompting evaluation of circulating genotypes in the postvaccine introduction era in Ghana.
Population
369 children less than 5 years of age with acute gastroenteritis visiting Ashaiman Polyclinic
Key result
Among 369 children under 5 years with acute gastroenteritis in Ghana, 39% tested positive for rotavirus, with G3P[6], G12P[8], G1P[8], and G9P[4] accounting for 68% of characterized strains.
Authors
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Rotavirus prevalence remains high in post-vaccine Ghana; extends genotype surveillance data but leaves open vaccine effectiveness questions.
Cross-Sectional (n=369)
No
High prevalence and diversity of rotavirus genotypes, including unusual ones, were detected in Ghana during the postvaccine introduction era.
Letsa et al. (2019) conducted a cross-sectional in Acute gastroenteritis (n=369). Rotavirus infection was evaluated on Rotavirus antigen positivity by EIA. Among 369 children under 5 years with acute gastroenteritis in Ghana, 39% tested positive for rotavirus, with G3P[6], G12P[8], G1P[8], and G9P[4] accounting for 68% of characterized strains.