Key result
A distinctive erythematous rash on the soles and palms combined with early PCR testing facilitated the rapid diagnosis of Human parechovirus type 3 infection in a neonate with sepsis-like syndrome.
Case Report (n=1)
A distinctive erythematous rash on the soles and palms can aid in the early clinical diagnosis of HPeV3 infection in neonates presenting with sepsis-like syndrome.
Human parechovirus type 3 (HPeV3) is known to cause sepsis-like syndrome and meningoencephalitis in neonates and young infants. We herein report a neonatal case of sepsis-like syndrome due to HPeV3 infection, diagnosed using polymerase chain reaction (PCR), with a distinctive erythematous rash present mainly on the soles and palms that helped in the diagnosis of the disease. Combining the unique characteristics of rash and confirmation by PCR at the early stage of the disease led to the diagnosis of HPeV3, distinguishing it from sepsis and other critical disease conditions, and allowing for appropriate, rapid management.
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Shoji et al. (2012) conducted a case report in Human parechovirus type 3 (HPeV3) infection (n=1). Polymerase chain reaction (PCR) and clinical observation of rash was evaluated on Diagnosis of HPeV3. A distinctive erythematous rash on the soles and palms combined with early PCR testing facilitated the rapid diagnosis of Human parechovirus type 3 infection in a neonate with sepsis-like syndrome.
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