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Human parechovirus-3 (HPeV-3) infection causes neonatal meningoencephalitis and hepatitis-coagulopathy syndrome and cannot be detected by standard enteroviral PCR.
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Highlights HPeV-3 as an emerging pathogen causing severe neonatal syndromes that requires specific testing beyond standard enteroviral PCR.
Human parechovirus-3 (HPeV-3) is an emerging pathogen that has been described as a cause of neonatal sepsis. Human parechoviruses are a family of viruses closely related to enteroviruses; however, enteroviral PCR will not detect HPeVs. We present clinical details of neonatal meningoencephalitis and hepatitis-coagulopathy syndrome caused by HPeV-3 infection.
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Levorson et al. (2009) studied this question. Human parechovirus-3 (HPeV-3) infection causes neonatal meningoencephalitis and hepatitis-coagulopathy syndrome and cannot be detected by standard enteroviral PCR.
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