Key result
Human parechoviruses were detected in 2.3% of infants with suspected meningitis/encephalitis and 6.3% of children with gastroenteritis, with HPeV3 being a significant cause of systemic infection.
Population
397 infants aged less than 12 months evaluated for meningitis or encephalitis, and 271 children aged less…
Design
Cross-sectional
Authors
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Supports HPeV testing in young infants with CNS or GI illness; leaves open whether routine inclusion improves outcomes.
Cross-Sectional (n=668)
HPeV infection, particularly HPeV3, is a significant cause of hospital admission for systemic infection in young infants and should be included in routine enterovirus testing.
Piñeiro et al. (2010) conducted a cross-sectional in Suspected meningitis, encephalitis, or gastroenteritis (n=668). Human parechovirus (HPeV) infection was evaluated on HPeV detection rate in cerebrospinal fluid and stool samples. Human parechoviruses were detected in 2.3% of infants with suspected meningitis/encephalitis and 6.3% of children with gastroenteritis, with HPeV3 being a significant cause of systemic infection.
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