Why the study?
What are the clinical and epidemiological differences between human parechovirus and enterovirus infections in infants <1 month old?
Population
84 infants <1 month old with neurological or systemic symptoms in Spain
Comparison
Human parechovirus (HPeV) infection vs Enterovirus (EV) infection
Design
Cohort
Authors
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HPeV may present without pleocytosis in neonates unlike EV; hypothesis-generating for viral testing algorithms in febrile infants.
What are the clinical and epidemiological differences between human parechovirus and enterovirus infections in infants <1 month old?
HPeV accounts for approximately 10% of infections in infants <1 month with neurological or systemic symptoms, presenting mainly as fever without source and lacking CSF pleocytosis compared to EV.
Cabrerizo et al. (2015) studied this question.
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