In their Perspective, Valentine and Gralla summarize the emerging picture of a series of transport proteins that shuttle the toxic metal, copper, safely around the cell, delivering it to nascent enzymes that rely on copper for proper catalytic function. A report in this week9s issue by Pufahl et al. describes the delivery of copper to Fet3 by Atx1.
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Valentine et al. (1997) studied this question.
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