High Doses of Furosemide and Sodium in Hypertension

A clinical experience in the treatment of arterial hypertension based only on the administration of high doses of furosemide and sodium is reported. Ten cases of severe hypertension showed a decrease of their blood pressure from the mean value of 153.8 ± 9.7 to 121.1 ± 6.3 mm Hg. This effect was found to be significantly better than that previously obtained with the conventional antihypertensive therapy and was also followed by improvement in the complications of hypertension detected in several cases. No side effects were observed and the gross polyuria induced by the treatment was well tolerated. Orthostatic hypotension has not been observed.